Membranous glomerulonephritis secondary to syphilis

Membranous glomerulonephritis secondary to syphilis.

Stanley de Almeida Araújo, Luiz Flávio Giordano , Ariel Augusto de Britto Rosa , Paula Alves Santos do Carmo, Kinulpe Honorato-Sampaio a Escola de Medicina da Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil b Centro Especializado em Anatomia Patológica, Belo Horizonte, MG, Brazil c Hospital Universitário São José, Belo Horizonte, MG, Brazil d Centro de Microscopia da Universidade Fed...

Gastric Syphilis and Membranous Glomerulonephritis

Syphilis is a chronic systemic infectious disease caused by the bacterium Treponema pallidum. Gastric involvement and nephrotic syndrome are uncommon but well documented complications of syphilis, but the co-occurrence of these two complications in the same patient is extremely rare. Thus, because of their nonspecific presentation, suspicion of gastric syphilis (GS) and nephrotic syndrome is es...

Membranous glomerulonephritis in a patient with syphilis.

Sjögren Syndrome-Related Membranous Glomerulonephritis Progressing to Membranoproliferative Glomerulonephritis

We report a case of glomerulopathy in a 36-year-old Japanese woman with primary Sjögren syndrome (pSS). The first renal biopsy suggested membranous glomerulonephritis. However, repeat biopsy was performed after 16 years because of increased proteinuria, revealing membranoproliferative glomerulonephritis with mesangial deposits, subendothelial deposits, and subepithelial deposits. Immunofluoresc...

Mesangial cells in membranous glomerulonephritis.

Renal biopsies of seven patients with membranous glomerulonephritis were examined by light, electron, and immunofluorescence microscopy. All had characteristic changes of glomerular basement membranes, typically with bright granular membranous fluorescence of IgG and variable deposits of complement. Cellularity was normal or slightly increased due largely to mesangial cell proliferation. These ...